skills.rest
SciMate-AI
SciMate-AIOFFICIAL
Explore all skills by this author →
GitHub

interpro-database

Consolidate InterPro protein annotations for UniProt entries via REST API.

1|Updated Mar 11, 2026
Search Tags:#bioinformatics#annotation#domains#interpro#go-terms#proteins
One-click install
npx skills add https://github.com/SciMate-AI/scicli --skill interpro-database-scimate-ai
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: interpro-database
Source: https://github.com/SciMate-AI/scicli/tree/main/internal/skills/bundled/claude-scientific-skills/skills/interpro-database
Command: npx skills add https://github.com/SciMate-AI/scicli --skill interpro-database-scimate-ai

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes references (resource) components.

What problem does it solve?

InterPro consolidates protein family, domain, and GO-term data into a single queryable resource, streamlining functional annotation workflows.

Core Features & Use Cases

  • Integrates data from Pfam, PANTHER, PRINTS, SMART, SUPERFAMILY and more for automated protein annotation.
  • Retrieves GO terms, domain architectures, and evolutionary classifications to support literature reviews and pipeline building.
  • Use Case: A researcher uploads a list of UniProt IDs to obtain a unified annotation set for downstream enrichment analysis.

Quick Start

Query InterPro annotations for a UniProt ID via the REST API to fetch domains, GO terms, and family classifications.

Frequently Asked Questions about interpro-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve InterPro domain architectures and GO terms for a list of UniProt IDs?▼

InterPro unifies protein annotations by integrating family, domain, and GO-term data from member databases like Pfam and PANTHER. It solves the problem of fragmented functional annotation workflows by consolidating this data into a single queryable resource.

Can I batch query UniProt entries to get unified protein annotations and GO mappings?▼

InterPro unifies protein annotations by integrating family, domain, and GO-term data from member databases like Pfam and PANTHER. It solves the problem of fragmented functional annotation workflows by consolidating this data into a single queryable resource.

What is the best way to automate protein function annotation and evolutionary classification from multiple databases?▼

InterPro unifies protein annotations by integrating family, domain, and GO-term data from member databases like Pfam and PANTHER. It solves the problem of fragmented functional annotation workflows by consolidating this data into a single queryable resource.

Does retrieving InterPro annotations via the REST API require handling pagination for large protein datasets?▼

InterPro unifies protein annotations by integrating family, domain, and GO-term data from member databases like Pfam and PANTHER. It solves the problem of fragmented functional annotation workflows by consolidating this data into a single queryable resource.

What limitations exist when using the InterPro REST API for automated protein annotation?▼

InterPro unifies protein annotations by integrating family, domain, and GO-term data from member databases like Pfam and PANTHER. It solves the problem of fragmented functional annotation workflows by consolidating this data into a single queryable resource.

Related Skills

Explore More Education & Research Skills→
swaruplabswaruplab
94

interpro-database

Fetch InterPro annotations for UniProt proteins via REST API endpoints.

Community
Advanced
jaechang-hitsjaechang-hits
298

quickgo-database

Query the EBI QuickGO REST API for Gene Ontology terms and protein annotations.

Community
Intermediate
jaechang-hitsjaechang-hits
298

interpro-database

Query the InterPro REST API for protein domain architecture and family classifications.

Community
Intermediate
qinyan-aiqinyan-ai
48

interpro-database

Query InterPro REST API to map protein domains, families, and GO terms.

Community
Advanced