NCI-DTP-MolTarget

Query NCI-60 Molecular Target protein-expression records by gene, cell line, panel, or MOLTID.

130|4|Updated Mar 13, 2026

Search Tags:#bioinformatics #data-analysis #protein-expression #drug-target #cell-lines #nci-60 #molecular-targets

Ready to run

npx skills add https://github.com/QSong-github/DrugClaw --skill nci-dtp-moltarget

💬 Prompt for ChatGPT / Claude Chat▼

Please help me install this Agent Skill.
Skill: NCI-DTP-MolTarget
Source: https://github.com/QSong-github/DrugClaw/tree/main/skills/dti/molecular_targets_data
Command: npx skills add https://github.com/QSong-github/DrugClaw --skill nci-dtp-moltarget

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Query the NCI-60 Molecular Target (Protein) dataset to retrieve protein expression data for drug targets across cancer cell lines, enabling evidence-based target assessment and cross-referencing with gene identifiers.

Core Features & Use Cases

Auto-detects input type (gene symbol, cell line, cancer panel, or MOLTID) and returns relevant protein-expression records.
Supports queries for individual genes, cell lines (e.g., MCF7), cancer panels (e.g., Breast), or MOLTID records, with structured results suitable for downstream analysis.
Use Case: identify protein expression patterns of a target across multiple cell lines to gauge target relevance and prioritize validation experiments.

Quick Start

Provide a gene symbol (e.g., EGFR) to retrieve its NCI-60 protein-expression measurements, including values and experimental methods.

Frequently Asked Questions about NCI-DTP-MolTarget

High-intent search queries and answers about installing and using this skill.

FAQPage Schema

How do I retrieve NCI-60 protein expression data for a specific gene?▼

To retrieve NCI-60 protein expression data, provide a gene symbol like EGFR. The Skill auto-detects the input and returns matching protein-expression records with values, units, and experimental methods.

Can I query NCI-60 molecular targets using a cancer cell line name?▼

Yes, you can query NCI-60 molecular targets using a cell line like MCF7. The tool auto-detects cell line inputs and returns relevant protein-expression records for drug target analysis.

How do I get protein expression measurements for an entire cancer panel?▼

You can retrieve protein expression measurements for a cancer panel by providing the panel name, such as Breast. The Skill identifies the panel type and returns all matching protein target records.

What is the best way to analyze drug target protein expression across multiple cell lines?▼

The best way to analyze drug target protein expression is to query the NCI-60 dataset by gene symbol. This identifies expression patterns across multiple cell lines to help prioritize validation experiments.

Does this NCI-60 protein target query tool require external dependencies?▼

No, this NCI-60 protein target query tool requires no external dependencies. It loads from a local data file to expose search, summarize, and JSON-ready outputs for downstream analysis.

What format are the NCI-60 molecular target records returned in?▼

NCI-60 molecular target records are returned as structured, JSON-ready outputs. These include protein-expression values, units, and method details suitable for downstream bioinformatics data analysis.