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opentrons-integration

Automate Opentrons Flex and OT-2 liquid handling with Protocol API v2.

3|Updated Apr 17, 2026
Search Tags:#robotics#lab automation#opentrons#liquid handling#protocol automation
One-click install
npx skills add https://github.com/RamanEbrahimi/raman-marketplace --skill opentrons-integration-ramanebrahimi
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: opentrons-integration
Source: https://github.com/RamanEbrahimi/raman-marketplace/tree/main/plugins/agentic-research/skills/scientific-skills/opentrons-integration
Command: npx skills add https://github.com/RamanEbrahimi/raman-marketplace --skill opentrons-integration-ramanebrahimi

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires opentrons, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill streamlines Opentrons robot workflows, allowing users to write and execute protocols for liquid handling, hardware control, and labware management without manual intervention.

Core Features & Use Cases

  • Liquid Handling: Automate pipetting workflows with precision and control.
  • Hardware Control: Interface with temperature modules, magnetic modules, heater-shakers, and thermocyclers.
  • Labware Management: Configure labware and deck layouts for optimal robot performance.
  • Use Case: For example, users can write a protocol to perform a PCR setup with thermocycler control and automated pipetting, reducing manual labor and ensuring consistent results.

Quick Start

To begin, load your labware and pipettes, then execute the 'PCR Setup' protocol from the 'scripts/' directory.

Frequently Asked Questions about opentrons-integration

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I automate liquid handling protocols for Opentrons robots?▼

Automate liquid handling protocols using the Opentrons Protocol API v2 to control pipetting, labware setup, and hardware modules without manual intervention. This Skill provides scripts to execute these workflows on Flex and OT-2 robots.

Can I control temperature modules and thermocyclers with Opentrons API v2?▼

Yes, Opentrons API v2 supports hardware control for temperature modules, magnetic modules, heater-shakers, and thermocyclers. You can integrate these modules directly into your automated lab workflows.

What do I need to set up before running Opentrons protocol automation?▼

You need Python 3 and the opentrons protocol_api library installed. Once your environment is ready, load your labware and pipettes, then execute the provided protocol scripts to run your lab automation workflows.

Does this support both Opentrons Flex and OT-2 robots?▼

Yes, protocol automation via Opentrons API v2 supports both Flex and OT-2 robots. You can write and execute liquid handling and hardware control protocols tailored to either robot's hardware and software interfaces.

How do I configure labware and deck layouts for automated pipetting?▼

Configure labware and deck layouts within your Python protocol scripts using the Opentrons API v2. This ensures optimal robot performance and precise liquid handling during automated pipetting workflows.

What is the best way to run a PCR setup with automated pipetting and thermocycler control?▼

Use the provided PCR Setup protocol script in the scripts directory to perform automated pipetting and thermocycler control. This reduces manual labor and ensures consistent PCR preparation results on Opentrons robots.

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