What problem does it solve?
This Skill removes the manual friction of preparing and launching nf-core/pacsomatic analyses from matched tumor and normal BAM inputs, helping operators validate inputs, build reproducible launch artifacts, and avoid common setup mistakes.
Core Features & Use Cases
- Input validation: Checks patient and sample identifiers, BAM paths, optional index files, and the required choice of either a FASTA reference or a genome key.
- Launch preparation: Generates a pacsomatic-compatible samplesheet, a generated parameter file, and a ready-to-run launch script.
- Execution support: Handles dry runs, local execution, and scheduler submission for LSF, Slurm, PBS, and SGE.
- Troubleshooting workflow: Surfaces missing runtime tools, warns about dependency gaps, and reports the submitted job ID when available.
Quick Start
Ask the pacsomatic skill to validate your tumor and normal BAM inputs, choose either a FASTA reference or a genome key, generate the launch artifacts, and perform a dry run or submission as needed.