signac

Community

Integrate ATAC with Seurat chromatin insights.

AuthorCHENyiru3
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Signac enables scalable chromatin accessibility analysis and seamless integration with Seurat to unify ATAC and RNA workflows in a single framework.

Core Features & Use Cases

  • Chromatin accessibility analysis with Signac, integration with Seurat, and gene activity inference.
  • Multi-modal workflows combining ATAC with RNA data for joint visualization and interpretation.
  • Best practices for setting up Signac objects, TF-IDF normalization, dimensionality reduction, and visualization.

Quick Start

Install Signac and Seurat, load libraries, and begin analyzing a scATAC-seq dataset by creating a Seurat object with a chromatin assay and computing gene activity.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: signac
Download link: https://github.com/CHENyiru3/AI-Skills-Collections/archive/main.zip#signac

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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