sirs-criteria

Calculate SIRS scores from first-day ICU data for adult datasets.

40|17|Updated Oct 27, 2025
One-click install
npx skills add https://github.com/hannesill/m4 --skill sirs-criteria
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: sirs-criteria
Source: https://github.com/hannesill/m4/tree/main/src/m4/skills/clinical/sirs-criteria
Command: npx skills add https://github.com/hannesill/m4 --skill sirs-criteria

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) components.

What problem does it solve?

The Systemic Inflammatory Response Syndrome (SIRS) Criteria Calculation provides a dataset-ready method to quantify systemic inflammation in ICU patients, enabling historical sepsis research and comparisons across definitions.

Core Features & Use Cases

  • Score 0-4: Compute the SIRS score and per-component scores (temperature, heart rate, respiratory rate, WBC) for each ICU stay, using the first day data and imputation rules.
  • Dataset readiness: Includes explicit guidance and references for MIMIC-IV derived tables (mimiciv_derived.sirs) and cross-definition comparisons with Sepsis-3; notes on eICU availability.
  • Use cases: Historical sepsis studies, inflammatory-response quantification, and legacy quality metrics; supports dataset-agnostic usage with context on pediatric thresholds where applicable.

Quick Start

Run the SIRS calculation on your ICU dataset to generate per-stay scores (0-4) and component breakdowns.

Frequently Asked Questions about sirs-criteria

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I calculate the SIRS score for ICU stays in MIMIC-IV?

Calculating the SIRS score in MIMIC-IV involves applying the criteria to first-day ICU data to generate a 0-4 score per stay. It evaluates temperature, heart rate, respiratory rate (handling PaCO2), and WBC with bands when available.

What is the SIRS criteria and how does it quantify systemic inflammatory response syndrome?

The SIRS criteria quantifies systemic inflammatory response syndrome by scoring four physiological components: temperature, heart rate, respiratory rate, and WBC. It generates a 0-4 score per ICU stay to support historical sepsis research and inflammatory-response analysis.

How are missing vital signs handled when computing SIRS scores for clinical datasets?

When computing SIRS scores, missing components are treated as normal unless explicitly null. This imputation rule ensures absent first-day ICU data does not artificially inflate the systemic inflammatory response syndrome score.

Can I compare SIRS-based sepsis definitions with Sepsis-3 criteria using ICU data?

Yes, you can compare SIRS-based definitions with Sepsis-3 criteria. The SIRS calculation supports cross-definition comparisons by providing dataset-ready per-stay scores and component breakdowns for historical sepsis research in adult ICU datasets.

Does SIRS calculation work with eICU datasets or is it limited to MIMIC-IV?

The SIRS calculation is optimized for adult ICU datasets like MIMIC-IV and includes notes on eICU availability. It is dataset-agnostic but requires first-day clinical data including temperature, heart rate, respiratory rate, and WBC.