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tooluniverse-clinical-guidelines

Search and retrieve clinical practice guidelines from NICE, WHO, NCCN, AHA, ADA, and CPIC sources.

1.7k|254|Updated Mar 3, 2025
Search Tags:#pharmacogenomics#evidence-based medicine#cpic#clinical guidelines#treatment recommendations#medical search#nice
One-click install
npx skills add https://github.com/mims-harvard/ToolUniverse --skill tooluniverse-clinical-guidelines
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: tooluniverse-clinical-guidelines
Source: https://github.com/mims-harvard/ToolUniverse/tree/main/plugins/tooluniverse/skills/tooluniverse-clinical-guidelines
Command: npx skills add https://github.com/mims-harvard/ToolUniverse --skill tooluniverse-clinical-guidelines

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Finding trustworthy, up-to-date clinical practice guidelines requires searching dozens of separate society websites and databases, then reconciling conflicting recommendations and evidence grades across sources.

Core Features & Use Cases

  • Multi-source guideline search: Query 12+ authoritative sources (NICE, WHO, GIN, TRIP, SIGN, CMA, USPSTF/CTFPHC, OpenAlex, PubMed, EuropePMC) in parallel with a source-prioritization hierarchy.
  • Society-specific retrieval: Dedicated workflows for ADA diabetes standards, AHA/ACC cardiology guidelines, NCCN oncology patient guidelines, MAGICapp living guidelines, and CPIC pharmacogenomic dosing recommendations.
  • Clinical reasoning frameworks: Built-in protocols for diagnostic test selection (sensitivity vs specificity tradeoffs), evidence grading interpretation, surgical decision-making, and clinical MCQ verification.
  • Use Case: A clinician asks whether SGLT2 inhibitors are recommended for HFpEF. The skill searches NICE, GIN, and AHA/ACC in parallel, retrieves full-text recommendations, and synthesizes a cited summary with evidence grades and publication years.

Quick Start

Search clinical guidelines for first-line treatment of type 2 diabetes and summarize the recommendations with evidence grades and sources.

Frequently Asked Questions about tooluniverse-clinical-guidelines

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I search clinical practice guidelines from NICE and WHO?▼

Use NICE_Clinical_Guidelines_Search and WHO_Guidelines_Search with a query and limit parameter, running them in parallel with GIN and TRIP searches. NICE and WHO results are prioritized because they are evidence-graded and regularly updated.

How do I get CPIC pharmacogenomic dosing recommendations for a gene?▼

Call CPIC_get_gene_info for the gene overview, then CPIC_get_gene_drug_pairs, then CPIC_list_guidelines to find the guidelineId, and finally CPIC_get_recommendations with that integer guideline_id. Deduplicate results by phenotype before presenting.

Which guideline sources should be searched first for a clinical question?▼

Start with NICE, GIN, and TRIP in parallel, then add the relevant society tool such as AHA/ACC for cardiology, ADA for diabetes, or NCCN for oncology. Always query at least three sources and check publication dates for superseded guidance.

Why does NCCN_search_guidelines not return full guideline text?▼

NCCN_search_guidelines returns JNCCN PubMed abstracts about guidelines, not the proprietary NCCN guideline content. For patient-facing full text, use NCCN_list_patient_guidelines and pass the full URL to NCCN_get_patient_guideline.

What are the limitations of WHO and NCI guideline tools?▼

WHO_Guidelines_Search has unreliable topic filtering and may return unrelated publications, so supplement it with GIN. NCI_search_cancer_resources catalogs research tools and datasets, not clinical guidelines, and uses q and size parameters instead of query and limit.

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