clinpgx-database

Query gene-drug interactions, CPIC guidelines, allele functions, and drug labels from the ClinPGx database.

1|Updated Jan 14, 2026
One-click install
npx skills add https://github.com/Sologa/codex-pipeline --skill clinpgx-database-sologa
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: clinpgx-database
Source: https://github.com/Sologa/codex-pipeline/tree/main/.codex/skills/clinpgx-database
Command: npx skills add https://github.com/Sologa/codex-pipeline --skill clinpgx-database-sologa

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides access to comprehensive pharmacogenomics data, enabling precision medicine by understanding how genetic variations affect drug response.

Core Features & Use Cases

  • Gene-Drug Interaction Queries: Retrieve information on how specific genes influence drug efficacy and metabolism.
  • CPIC Guideline Access: Get evidence-based clinical practice guidelines for genotype-guided drug prescribing.
  • Allele and Variant Information: Query detailed data on genetic variants, their functions, and population frequencies.
  • Use Case: A clinician can use this Skill to quickly look up recommendations for prescribing clopidogrel to a patient with a known CYP2C19 genotype.

Quick Start

Use the clinpgx-database skill to find gene-drug interactions for CYP2D6 and codeine.

Frequently Asked Questions about clinpgx-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I query pharmacogenomics data for gene-drug interactions like CYP2D6 and codeine?

To query pharmacogenomics data for gene-drug interactions like CYP2D6 and codeine, use this Skill to programmatically access the ClinPGx database. It retrieves specific information on how genetic variations influence drug efficacy and metabolism.

Can I get CPIC guidelines for genotype-guided drug prescribing using this tool?

Yes, you can get CPIC guidelines for genotype-guided drug prescribing. The Skill provides access to evidence-based clinical practice guidelines from CPIC, PharmGKB, and PharmCAT to support clinical decision making.

What pharmacogenomics data sources are integrated for clinical decision support?

The pharmacogenomics data sources integrated for clinical decision support include PharmGKB, CPIC, and PharmCAT. This integration provides comprehensive allele functions, variant frequencies, and drug labels for precision medicine applications.

Does this pharmacogenomics database tool work with Python requests?

Yes, this pharmacogenomics database tool works with Python requests. The Skill requires the requests library as its sole dependency to programmatically query gene-drug interactions and retrieve clinical guideline data.

How do I find allele functions and population frequencies for genetic variants?

To find allele functions and population frequencies for genetic variants, query the ClinPGx database through this Skill. It enables detailed lookups of genetic variants and their specific functions to facilitate genotype-guided dosing decisions.

What is the best way to retrieve clopidogrel recommendations for a CYP2C19 genotype?

The best way to retrieve clopidogrel recommendations for a CYP2C19 genotype is by querying this Skill. It accesses clinical practice guidelines to provide precise dosing recommendations for patients with known genetic profiles.