Query GTEx REST API v2 for tissue-specific gene expression, eQTLs, and sQTLs.
npx skills add https://github.com/biomaps-infra/blender-opencode --skill db-gtex
Please help me install this Agent Skill. Skill: db-gtex Source: https://github.com/biomaps-infra/blender-opencode/tree/main/.opencode/skills/db-gtex Command: npx skills add https://github.com/biomaps-infra/blender-opencode --skill db-gtex
This Skill helps researchers interpret genetic variants by querying the Genotype-Tissue Expression (GTEx) database to understand gene expression patterns and regulatory effects across different human tissues.
Query GTEx for the median expression of the gene APOE across all tissues.
High-intent search queries and answers about installing and using this skill.
To retrieve tissue-specific gene expression data, you query the GTEx REST API v2 to get median expression levels measured in TPM across 54 human tissues. This allows you to compare expression patterns for genes like APOE across different tissue types.
You can identify eQTLs and sQTLs by querying the GTEx REST API v2 for specific genetic variants or genes. This retrieves associations linking variants to gene expression or splicing variations within specific human tissues.
Interpret non-coding GWAS variants by querying the GTEx database to find overlapping eQTLs in relevant tissues. This links the variant to potential target genes and reveals tissue-specific genetic associations with gene expression.
Yes, you can retrieve a list of eGenes per tissue by querying the GTEx REST API v2. This provides a comprehensive list of genes showing significant expression quantitative trait loci within your specified tissue.
Querying GTEx for tissue-specific eQTL analysis requires the requests library to interact with the GTEx REST API v2 and pandas to structure the retrieved expression and genetic association data for analysis.
Yes, the GTEx API supports comparing gene expression between tissues like brain and liver by retrieving median TPM levels across 54 distinct human tissues. This allows direct comparison of regulatory effects and expression patterns across tissue types.
nahisahoExtract GTEx tissue-specific gene expression and eQTL data via REST API v2.
google-deepmindRetrieve GTEx baseline RNA expression and single-tissue eQTL associations for genes and genomic regions.
NeuroAIHubRetrieve RNA expression baselines and eQTL associations from the GTEx Portal API.
yf8578Query the GTEx REST API v2 for tissue-specific gene expression and eQTL data.
