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scientific-gtex-tissue-expression

Extract GTEx tissue-specific gene expression and eQTL data via REST API v2.

3|1|Updated Feb 11, 2026
Search Tags:#expression-analysis#eqtl#gtex#tissue-expression#eqtl-lookups#multitissue-comparison
One-click install
npx skills add https://github.com/nahisaho/satori --skill scientific-gtex-tissue-expression
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: scientific-gtex-tissue-expression
Source: https://github.com/nahisaho/satori/tree/main/src/.github/skills/scientific-gtex-tissue-expression
Command: npx skills add https://github.com/nahisaho/satori --skill scientific-gtex-tissue-expression

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

GTEx tissue-specific expression patterns, eQTL lookups, and cross-tissue comparisons are essential for understanding gene regulation. This skill provides programmatic access to GTEx Portal REST API v2 to retrieve median TPM expressions and variant associations across multiple tissues.

Core Features & Use Cases

  • Retrieve tissue-specific gene expression (median TPM) across tissues via GTEx Portal API v2.
  • Perform eQTL lookups to link variants with expression differences in given tissues.
  • Compare gene expression across multiple tissues to identify tissue-specific patterns and potential regulatory effects.

Quick Start

Query a gene (symbol or Ensembl ID) to retrieve tissue-specific expression and eQTL data across GTEx tissues.

Frequently Asked Questions about scientific-gtex-tissue-expression

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve GTEx tissue-specific gene expression data for multiple genes?▼

Perform eQTL lookups by querying the GTEx Portal REST API v2 with variant and tissue parameters to link genetic variants with expression differences. This identifies regulatory effects of specific variants on gene expression across tissues.

What is the best way to compare gene expression patterns across multiple GTEx tissues?▼

You do not need specialized dependencies to use this GTEx tissue expression skill. It directly interacts with the GTEx Portal REST API v2 to extract median TPM values and eQTL information without requiring external component setups.

Can I use Ensembl IDs instead of gene symbols for GTEx eQTL lookups?▼

Yes, you can use Ensembl IDs instead of gene symbols for GTEx eQTL lookups. The skill accepts both gene symbols and Ensembl IDs as valid query inputs to retrieve tissue-specific expression and eQTL data from the GTEx Portal REST API v2.

What limitations exist when analyzing variant effects on expression using GTEx data?▼

A limitation when analyzing variant effects on expression is that the skill relies exclusively on GTEx Portal API v2 data, restricting lookups to median TPM and variant associations within available GTEx tissues rather than supporting custom datasets.

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