disease-modeler
CommunityMap OM biology to targets and candidates
Education & Research#drug repurposing#target validation#oral mucositis#disease modeling#phase mapping#cancer therapy safety#gene-disease logic
AuthorOpenSourcePharmaFoundation
Version1.0.0
Installs0
System Documentation
What problem does it solve?
It helps you evaluate whether a proposed intervention for oral mucositis matches the disease’s actual pathobiology across its progression phases, so you don’t get misled by generic “anti-inflammatory” or “wound healing” labels.
Core Features & Use Cases
- OM phase mapping: Assign a candidate’s mechanism to the Sonis 5-phase model (Initiation through Healing) and judge phase-appropriate relevance and strength.
- Therapeutic gap analysis: Identify which OM phases are well-covered versus underserved by a set of candidates, and infer what kind of mechanism would fill the biggest gap.
- Disease relevance scoring: Assess timing (prevention vs acute treatment vs healing support), conflict with underlying cancer therapy, and whether the mechanism is truly tied to OM biology.
- Patient context assessment: Evaluate suitability by OM subtype (radiation, chemo, transplant, targeted therapy, immunotherapy) and practical delivery constraints.
Quick Start
Use the disease-modeler skill to assess a candidate mechanism against the OM phase model and produce a structured phase-by-phase rationale for the right timing and patient context.
Dependency Matrix
Required Modules
None requiredComponents
Standard package💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: disease-modeler Download link: https://github.com/OpenSourcePharmaFoundation/ospf-ayurveda-kg/archive/main.zip#disease-modeler Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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