interpro-database

Query the InterPro REST API for protein family, domain, and functional site annotations.

1|Updated Mar 12, 2026
One-click install
npx skills add https://github.com/yf8578/clawomics --skill interpro-database-yf8578
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: interpro-database
Source: https://github.com/yf8578/clawomics/tree/main/skills/interpro-database
Command: npx skills add https://github.com/yf8578/clawomics --skill interpro-database-yf8578

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill helps researchers understand protein function, identify protein families and domains, and map sequences to biological databases, streamlining bioinformatics analysis.

Core Features & Use Cases

  • Protein Function Prediction: Determine the likely functions of unknown proteins.
  • Domain Architecture Analysis: Visualize and analyze the structural and functional units within a protein sequence.
  • GO Term Mapping: Associate proteins with Gene Ontology terms for functional classification.
  • Use Case: Given a novel protein sequence, use this Skill to identify its known domains, predict its function, and find relevant Gene Ontology terms.

Quick Start

Use the interpro-database skill to get all InterPro entries for the UniProt ID P04637.

Frequently Asked Questions about interpro-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve protein family and domain annotations using a UniProt ID?

Domain architecture analysis maps structural and functional units within a protein sequence to identify known domains. It facilitates protein function prediction and evolutionary classification by retrieving entries from the InterPro database.

Can I map Gene Ontology terms to an unknown protein sequence?

InterPro integrates data from 13 member databases to provide comprehensive protein family, domain, and functional site annotations. This extensive integration facilitates accurate evolutionary classification and domain architecture analysis.

What is the best way to predict protein function for novel sequences?

InterPro integrates data from 13 member databases to provide comprehensive protein family, domain, and functional site annotations. This extensive integration facilitates accurate evolutionary classification and domain architecture analysis.

Do I need the requests library to access InterPro programmatic data?

InterPro integrates data from 13 member databases to provide comprehensive protein family, domain, and functional site annotations. This extensive integration facilitates accurate evolutionary classification and domain architecture analysis.