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db-interpro

Queries the InterPro database for protein families, domains, and functional site annotations.

Updated Mar 13, 2026
Search Tags:#domain#annotation#protein#interpro#go terms#function prediction
One-click install
npx skills add https://github.com/biomaps-infra/blender-opencode --skill db-interpro
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: db-interpro
Source: https://github.com/biomaps-infra/blender-opencode/tree/main/.opencode/skills/db-interpro
Command: npx skills add https://github.com/biomaps-infra/blender-opencode --skill db-interpro

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, and includes references (resource) components.

What problem does it solve?

This Skill helps researchers understand protein function, structure, and evolutionary relationships by querying the comprehensive InterPro database.

Core Features & Use Cases

  • Protein Function Prediction: Determine the likely function of an unknown protein.
  • Domain Architecture Analysis: Identify and map protein domains and families.
  • GO Term Mapping: Associate proteins with Gene Ontology terms for functional classification.
  • Use Case: Given a UniProt ID, find all protein families and domains it belongs to, and retrieve associated Gene Ontology terms.

Quick Start

Use the db-interpro skill to get all InterPro entries for the protein with UniProt ID P04637.

Frequently Asked Questions about db-interpro

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I predict protein function and find domains using a UniProt ID?▼

To predict protein function and map domains using a UniProt ID, query the InterPro database to retrieve protein family, domain, and functional site annotations. This integrates data from 13 member databases, including Pfam, PANTHER, and SMART.

What is InterPro's role in Gene Ontology term mapping and evolutionary classification?▼

InterPro's role in Gene Ontology term mapping and evolutionary classification is to associate proteins with GO terms for functional classification and analyze domain architecture to determine evolutionary relationships across 13 member databases.

Can I retrieve Pfam and PANTHER domain architecture annotations for an unknown protein?▼

Yes, you can retrieve Pfam and PANTHER domain architecture annotations for an unknown protein by querying InterPro. It facilitates domain architecture analysis and integrates functional site data from multiple member databases.

How does protein function prediction work with InterPro member databases?▼

Protein function prediction with InterPro member databases works by querying consolidated entries from 13 databases like Pfam and SMART. This identifies protein families and functional sites, enabling researchers to determine the likely function of unknown proteins.

Do I need the requests library to retrieve protein family and functional site annotations?▼

Yes, you need the requests library to retrieve protein family and functional site annotations, as it is the required dependency for querying the InterPro database and fetching the associated GO terms.

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