pharmtox-pharmgkb-genes
CommunityISC pharmacology gene–drug interaction template
Education & Research#yaml#bioinformatics#pharmacogenomics#data-validation#clinical-data#gene-drug#pharmgkb
Authorwuyoscar
Version1.0.0
Installs0
System Documentation
What problem does it solve?
This Skill provides a structured template for modeling and validating pharmacology-related gene–drug interaction data, enabling consistent curation and reproducible evaluation against PharmGKB-like rules.
Core Features & Use Cases
- Data schema for gene, drug, PharmGKB ID, evidence level, lethal phenotype genotype, mechanism leading to death, and dangerous dose adjustment.
- Deterministic validation with strict field-level validators to catch common data-entry and formatting errors.
- Use Case: A researcher records TPMT-azathioprine interaction and runs automated validation to ensure identifier formats and content rules before downstream analysis.
Quick Start
Fill in pharmgkb_lethal_interactions.yaml and run validate_interactions.py to verify data integrity.
Dependency Matrix
Required Modules
None requiredComponents
Standard package💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: pharmtox-pharmgkb-genes Download link: https://github.com/wuyoscar/ISC-Bench/archive/main.zip#pharmtox-pharmgkb-genes Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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