scientific-protein-structure-analysis

Retrieve protein structures from PDB, AlphaFold DB, and PDBe for quality assessment and docking preparation.

3|1|Updated Feb 11, 2026
One-click install
npx skills add https://github.com/nahisaho/satori --skill scientific-protein-structure-analysis
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: scientific-protein-structure-analysis
Source: https://github.com/nahisaho/satori/tree/main/src/.github/skills/scientific-protein-structure-analysis
Command: npx skills add https://github.com/nahisaho/satori --skill scientific-protein-structure-analysis

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Protein structure analysis is streamlined by retrieving data from PDB, AlphaFold DB, and PDBe, then evaluating quality, identifying domains, and preparing structures for docking and functional interpretation.

Core Features & Use Cases

  • Retrieve protein structures from PDB, AlphaFold DB, and PDBe.
  • Assess structure quality (resolution, pLDDT, Ramachandran) and map domain architecture.
  • Detect binding sites and prepare structures for docking or comparative analysis.
  • Integrate with ToolUniverse Protein Structure Retrieval and claude-scientific-skills PDB/AlphaFold pipelines for end-to-end workflows.

Quick Start

Provide the target protein identifier (UniProt ID, gene symbol, or PDB ID), and the skill will fetch, evaluate, and prepare structure data for downstream analysis.

Frequently Asked Questions about scientific-protein-structure-analysis

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve protein structures from PDB and AlphaFold DB for analysis?

Retrieve protein structures by providing a UniProt ID, gene symbol, or PDB ID to fetch data from PDB, AlphaFold DB, and PDBe. The skill evaluates quality, extracts structural features, and prepares structures for docking and functional interpretation.

What's the best way to assess protein structure quality using pLDDT and resolution?

Assess protein structure quality by evaluating pLDDT scores, resolution, and Ramachandran plots. The skill maps domain architecture and detects binding sites to support functional interpretation and docking preparation.

Can I prepare AlphaFold structures for molecular docking workflows?

Yes, you can prepare AlphaFold structures for docking. The skill detects binding sites, assesses quality metrics like pLDDT, and generates prepared structures and structured reports suitable for downstream drug design or comparative analysis.

Does protein structure analysis support binding site detection and domain mapping?

Protein structure analysis supports binding site detection and domain mapping by integrating ToolUniverse Protein Structure Retrieval and claude-scientific-skills PDB/AlphaFold pipelines. It evaluates quality and maps domain architecture across typical drug design scenarios.

How do I analyze protein structures for functional interpretation and drug design?

Analyze protein structures for functional interpretation by retrieving data from PDB, AlphaFold DB, and PDBe. The skill applies quality assessment, structural feature extraction, and binding site detection to generate structured reports supporting drug design studies.

What protein identifiers do I need to start PDB and AlphaFold structure retrieval?

To start PDB and AlphaFold structure retrieval, you need a UniProt ID, gene symbol, or PDB ID. The skill fetches, evaluates, and prepares structure data for downstream analysis workflows.