antigenomicsantigenomicsOfficialยท6 Agent Skills Included

vdjdb-db

Curate and validate T-cell receptor specificity database submissions

Extracts T-cell receptor antigen specificity records from papers, spreadsheets, and sequencing files into standardized database tables. Normalizes gene names, MHC alleles, and species labels to IMGT and VDJdb conventions, then runs quality checks to catch duplicates and errors. Eliminates manual data cleaning and inconsistent naming across immunology research submissions.
npx skills add antigenomics/vdjdb-db --all -g -y

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Frequently Asked Questions

FAQPage Schema
How to install vdjdb-db?โ–ผ

Run `npx skills add antigenomics/vdjdb-db --all -g -y` in your terminal to install all curation skills globally.

What is VDJdb used for?โ–ผ

VDJdb is a curated database of T-cell receptor sequences with known antigen specificity, used by immunology researchers to study how T cells recognize epitopes in specific MHC contexts.

How do I submit new TCR data to VDJdb?โ–ผ

The skills guide you through extracting records from source files, formatting them to the VDJdb specification, proofreading for errors, and publishing each chunk with a linked GitHub issue.

Can it fix wrong gene or allele names?โ–ผ

Yes. It validates V/D/J gene names against IMGT references and HLA alleles against official allele tables, then converts outdated or non-standard names automatically.

Do I need bioinformatics experience to use it?โ–ผ

Basic familiarity with TCR data helps, but the skills handle the technical validation, naming rules, and quality checks based on your plain-English instructions.

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