vdjdb-db
Curate and validate T-cell receptor specificity database submissions
All Skills in This Repository (6)
Pure Emerald Level Indicatorsvdjdb-proofread
Validate VDJdb chunk files for quality control and data consistency.
vdjdb-publish
Create and update GitHub issues for VDJdb data chunks.
vdjdb-harmonize
Normalize antigen.gene and antigen.species fields in VDJdb chunks to canonical naming.
vdjdb-format
Normalize VDJdb TSV chunks to VDJdb and IMGT standards.
vdjdb-extract
Extract TCR:pMHC specificity data into VDJdb-compatible TSV chunks.
vdjdb-duplicates
Identify and classify duplicate TCR records in VDJdb databases using Python.
Frequently Asked Questions
FAQPage SchemaHow to install vdjdb-db?โผ
Run `npx skills add antigenomics/vdjdb-db --all -g -y` in your terminal to install all curation skills globally.
What is VDJdb used for?โผ
VDJdb is a curated database of T-cell receptor sequences with known antigen specificity, used by immunology researchers to study how T cells recognize epitopes in specific MHC contexts.
How do I submit new TCR data to VDJdb?โผ
The skills guide you through extracting records from source files, formatting them to the VDJdb specification, proofreading for errors, and publishing each chunk with a linked GitHub issue.
Can it fix wrong gene or allele names?โผ
Yes. It validates V/D/J gene names against IMGT references and HLA alleles against official allele tables, then converts outdated or non-standard names automatically.
Do I need bioinformatics experience to use it?โผ
Basic familiarity with TCR data helps, but the skills handle the technical validation, naming rules, and quality checks based on your plain-English instructions.
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