exon-researchOfficial·19 Agent Skills Included

genomi

Private local DNA analysis, variant evidence, and health insights

Parses raw DNA files from VCF, BAM, FASTQ, and consumer tests like 23andMe into a private local genome index. Answers questions about variants, disease risk, ancestry, medication response, and nutrition using ClinVar, GWAS, gnomAD, and polygenic scores. Keeps all genetic data on your machine with no cloud uploads, and builds a full evidence dashboard from your genome.

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npx skills add exon-research/genomi --all -g -y

All Skills in This Repository (19)

Pure Emerald Level Indicators

📦 In Repo

exon-research

genomi

Analyze local genome data with natural language queries for genetic insights.

journal

Manage investigation memory by linking Genomi evidence and research findings.

pharmacogenomics

Analyzes drug-response and pharmacogenomic questions using public PGx evidence and local genotype data.

clinvar

Build candidate landscapes and inventories from exact ClinVar variant matches.

prs

Apply published polygenic scores to personal DNA and calculate raw weighted scores.

journal-source-research

Review academic journal evidence and record findings into Genomi context.

genomi-gnomad

Fetch population allele frequencies for a specified variant from gnomAD.

functional-genomics

Retrieve and analyze perturbation evidence from BioGRID ORCS and DepMap.

analytical-grounding

Retrieve pathway members, cell-type markers, and genomic interval overlaps from biological databases.

genomi-decode

Assembles a comprehensive Genomi Dashboard.html from active genome data and Genomi capabilities.

variant-evidence

Analyze genetic variants using Active Genome Index and public genetics databases.

ancestry

Project genome data onto 1000 Genomes reference panels for ancestry analysis.

Official

Intermediate

Frequently Asked Questions

FAQPage Schema

How to install Genomi?▼

Run `npx skills add exon-research/genomi --all -g -y` in your terminal to install all skills in this suite globally.

How to analyze my 23andMe raw data privately?▼

Give your agent the local file path and Genomi parses it into a private on-device genome index. Your DNA data never leaves your machine or gets uploaded to any cloud service.

Can Genomi tell me about medication response from my DNA?▼

Yes. The pharmacogenomics skill checks your genome against ClinPGx guidelines, FDA labels, and PGxDB evidence to explain how your variants affect drug response, with clinical confirmation always recommended.

Does Genomi work with Claude Code and other MCP hosts?▼

Yes. Genomi runs as an MCP server and works with Claude Code, Codex, OpenClaw, Hermes, and any MCP-capable host.

Can I use Genomi without a genetics background?▼

Yes. You ask plain-English questions like 'am I at risk for Alzheimer's?' and your agent gathers the right evidence, explains limitations, and flags when clinical confirmation is needed.